Coming to top performers this year, Galena Biopharma Inc (NASDAQ:GALE) is one of the top gainers with a year-to-date performance of 16.99%. The stock, as of last close, traded 316.28% up from its 52 week low and was 49.44% behind its 52 week high. Its latest closing price was 5.30% above the SMA200 while the distance from SMA 50 and SMA 20 was -2.72% and +2.11% respectively.

Another sharp gainer Dendreon Corporation (NASDAQ:DNDN) has YTD performance up at 13.61%. Its price, as of the latest close, was up 62.87% compared with the 52 week low and was 64.73% below the 52 week high.The stock’s latest closing price was down -5.61%  from the average-price of 200 days while it kept its distance from the SMA 50 at +30.92% and +16.11% compared with the SMA 20.

Sequenom, Inc.(NASDAQ:SQNM) has shown an uptrend of 11.04% this year with a monthly performance of 5.44% and 3-month performance up 50.72%. Its latest closing price was +30.55% up from an average-price of 200 days while it maintained a distance from the SMA 50 at +25.35% and +10.43% compared with the SMA 20. The stock was up 97.36% from the 52 week low and was 10.29% below the 52 week high.

The year-to-date performance of Idenix Pharmaceuticals, Inc.(NASDAQ:IDIX) stands at 10.52% with an advance of +22.37% in the last three months and -27.07% in the previous twelve months. Its price, as of the latest close, was 60.00% up from the 52 week low and was 64.85% below the 52 week high. Its latest closing price was -25.28% down from an average-price of 200 days while it kept its distance from the SMA 50 at +16.03% and +7.16% compared with the SMA 20.

Sarepta Therapeutics Inc (NASDAQ:SRPT) so far this year has moved up 12.40% and its monthly performance stands at -0.58%. The stock was 778.79% up compared with the 52 week low and was 35.56% below the 52 week high. Its latest closing price was 114.20% up from an average-price of 200 days while it kept its distance from the SMA 50 at +12.71% and +13.19% compared with the SMA 20.

On the flip side, NPS Pharmaceuticals, Inc.(NASDAQ:NPSP) has been one of the worst performers in 2013 with a year-to-date performance of -2.86%. The stock, as of last close, traded 43.74% up from its 52 week low and was 21.21% behind its 52 week high. Its latest closing price was 7.24% up from the SMA200 while the distance from SMA 50 and SMA 20 was -6.39% and -5.67% respectively.

Another biggest loser Questcor Pharmaceuticals, Inc.(NASDAQ:QCOR) has a performance down -2.28%. Its price, as of the latest close, was up 53.60% compared with the 52 week low and was 55.01% below the 52 week high.The stock’s latest closing price was -27.94% down from an average-price of 200 days while it kept its distance from the SMA 50 at -1.36% and -6.25% compared with the SMA 20.

Celsion Corporation(NASDAQ:CLSN) so far this year has moved down -1.95% and its monthly performance stands at +2.95%. The stock was 392.64% up compared with the 52 week low and was 9.37% below the 52 week high. Its latest closing price was 98.35% up from an average-price of 200 days while it kept its distance from the SMA 50 at +23.30% and +0.84% compared with the SMA 20.

Illumina, Inc.(NASDAQ:ILMN) has shown a downtrend of -1.49% this year with a monthly performance of +5.80% and 3-month performance up +7.37%. Its latest closing price was +18.47% up from an average-price of 200 days while it maintained a distance from the SMA 50 at +7.30% and +1.94% compared with the SMA 20. The stock was up 90.67% compared with the 52 week low and was 3.93% below the 52 week high.

Arena Pharmaceuticals, Inc.(NASDAQ:ARNA) so far in 2013 declined -0.22% and its monthly performance stands at +4.41%. The share price was 496.03% up compared with the 52 week low and was 33.33% below the 52 week high. Its most recent closing price was 20.47% up from an average-price of 200 days while it kept its distance from the SMA 50 at +3.38% and +0.76% compared with the SMA 20.